Champions Path:
Olimpija Ljubljana (SVN) – HJK (FIN) v Crvena zvezda (SRB)/Spartak Trnava (SVK)
H. Beer-Sheva (ISR) – APOEL (CYP) v Astana (KAZ) – Dinamo Zagreb (CRO)
Cork (IRL) – Rosenborg (NOR) v Salzburg (AUT) – Shkëndija (MKD)
Legia (POL) – Dudelange (LUX) v Alashkert (ARM) – CFR Cluj (ROU)
Spartaks Jurmala (LVA) – Suduva (LTU) v Celtic (SCO) – AEK (GRE)
Sheriff (MDA) – Valur (ISL) v Qarabag (AZE) – BATE (BLR)
Malmö (SWE) – Vidi (HUN) v TNS (WAL) – Midtjylland (DEN)
Torpedo Kutaisi (GEO) – Kukës (ALB) v Ludogorets (BUL) – Zrinjski (BIH)
Main Path:
Sigma (CZE) – Kairat (KAZ) v Sevilla (ESP) – Žalgiris (LTU)
Apollon (CYP) – Dinamo Brest (BLR) v Vitesse (NED) – Basel (SUI)
Sarpsborg (NOR) – Rijeka (CRO) v Pyunik (ARM) – M. Tel-Aviv (ISR)
Jagiellonia (POL) – Gent (BEL) v Mariupol (UKR) – Bordeaux (FRA)
Nordsjælland (DEN) – Partizan (SRB) v Besiktas (TUR) – LASK (AUT)
Slovan Bratislava (SVK) – Rapid W. (AUT) v Hajduk Split (CRO) – FCSB (ROU)
Rangers (SCO) – Maribor (SVN) v Ufa (RUS) – Progrès (LUX)
H. Haifa (ISR) – Atalanta (ITA) v CSKA-Sofia (BUL) – København (DEN)
Dinamo Minsk (BLR) – Zenit (RUS) v Hibernian (SCO) – Molde (NOR)
Trencín (SVK) – Feyenoord (NED) v Sturm (AUT) – AEK Larnaca (CYP)
Genk (BEL) – Lech (POL) v Spartak Subotica (SRB) – Brøndby (DEN)
Olympiacos (GRE) – Luzern (SUI) v Istanbul Basaksehir (TUR)-Burnley (ENG)
Zorya (UKR) – Braga (POR) v Leipzig (GER) – U. Craiova (ROU).